Blar i forfatter "Svadberg, Anders"
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Nucleophilic Substitution Reactions for Positron Emission Tomography; Factors Influencing the Reactivity of [18F]Fluoride
Svadberg, Anders (Doctoral thesis; Doktorgradsavhandling, 2012-03-02)Clinical use of positron emission tomography (PET) is expanding from use of [18F]FDG to a wider spectrum of PET-tracers and proprietary PET radiopharmaceuticals. The development of new PET-tracers is however far from trivial and the radiochemistry is a major limiting factor. Nucleophilic substitution reactions with [18F]fluoride generally suffer from inconsistent labeling yields. There is a need to ...